Dr. Emdormi Rymbai

Qualification:

Area of Interest

Neuropharmacology, Toxicology, Drug Discovery & Development, Computational Pharmacology, Network Pharmacology, Diabetes Pharmacology, Cancer Pharmacology

Research Experience: 5 Years

1. Paper Presenter in Conference — International Conference on “Global Collaboration in Pharmaceuticals: Bridging Borders, Breaking Barriers (International)
   JSS College of Pharmacy, Ooty • 2024-03-15 to 2025-03-17
2. Paper Presenter in Conference — 9th International Congress of Society for Ethnopharmacology, India- SFEC-2022 (International)
   JSS College of Pharmacy, Mysuru • 2022-04-22 to 2022-04-24
3. Paper Presenter in Symposium — E-Symposium on Integrated Approaches to Drug Discovery and Development (National)
   MCOPS, Manipal • 2022-07-25 to 2022-07-27

Journal

1. Dhritiman Roy, Bibhuti Bhusan Kakoti, Emdormi Rymbai, "Pharmacophore-based approach for identifying compounds with myricetin-like pharmacophoric features as potential GSK3? inhibitors in Alzheimer’s disease", Discover Chemistry, vol. 3, pp. 1-26, 2026.
   Indexing: Google Scholar, • ISSN: 3005-1193
2. Das S, Das MK, Jamatia T, Bishwas NR, Roy D, Rymbai E, "Breaking barriers: targeted delivery of resveratrol in lung cancer using folate-integrated and pH-responsive hybrid nanocarriers", Future Journal of Pharmaceutical Sciences, vol. 11, pp. 1-38, 2025.
   Indexing: Scopus, • IF: 3.0
3. Sugumar D, Rymbai E, Selvaraj D, "Harnessing androgen receptor: Revolutionizing diabetes treatment in men with selective androgen receptor modulators", Medical Hypotheses, vol. 190, pp. 111427, 2025.
   Indexing: Scopus, • IF: 0.8
4. Sugumar D, Rymbai E, Kothandan R, Chakkittukandayil A, Krishnamurthy PT, Muthu S, Selvaraj D, "Protective Role of Harmol Against ?-Cell Toxicity And Glucose Dysregulation In Type 2 Diabetes Mellitus", European Journal of Pharmacology, vol. 1002, pp. 177825, 2025.
   Indexing: Scopus, • IF: 4.7
5. Yasmine J, Sola P, Rymbai E, Dutta BJ, Buragohain S, "Computational Phytochemical Screening for Parkinson's Disease Therapeutics: c-Abl and Beyond", Computational Biology and Chemistry, vol. 116, pp. 108370, 2025.
   Indexing: Scopus, • IF: 3.1
6. Rymbai E, Sugumar D, Chakkittukandiyil A, Kothandan R, Selvaraj D, "Molecular insights into the potential effects of selective estrogen receptor ? agonists in Alzheimer's and Parkinson's diseases", Cell Biochemistry and Function, vol. 43, pp. e4014, 2025.
   Indexing: Scopus, • IF: 2.7
7. Chakkittukandiyil A, Sajini DV, Rymbai E, Sugumar D, Mathew J, Arumugam S, Ramachandran V, Selvaraj D, "Synthesis and evaluation of novel ethyl ferulate derivatives as potent Keap1 inhibitors to activate the Nrf2/ARE pathway in Parkinson's disease", Toxicology and Applied Pharmacology., vol. 494, pp. 117172, 2025.
   Indexing: Scopus, • IF: 3.4
8. Sugumar D, Ghosh R, Rymbai E, Chandrasekaran J, Krishnamurthy PT, P RS, Sahu S, Selvaraj D, "Ligandrol Ameliorates High-Fat Diet–and Streptozotocin-Induced Type 2 Diabetes Mellitus and Prevents Pancreatic Islets Degeneration", ASSAY and Drug Development Technologies, vol. 22, pp. 397-408, 2024.
   Indexing: Scopus, • IF: 1.7
9. Rymbai E, Roy D, Jupudi S, Srinivasadesikan V, "The identification of c-Abl inhibitors as potential agents for Parkinson’s disease: a preliminary in silico approach", Molecular Diversity, vol. 28, pp. 4051-4065, 2024.
   Indexing: Scopus, • IF: 3.8
10. Arumugam M, Pachamuthu RS, Rymbai E, Jha AP, Rajagopal K, Kothandan R, Muthu S, Selvaraj D, "Gene network analysis combined with preclinical studies to identify and elucidate the mechanism of action of novel irreversible Keap1 inhibitor for Parkinson’s disease", Molecular Diversity, vol. 33, pp. 1-8, 2024.
    Indexing: Scopus, • IF: 3.8
11. Rymbai E, Sugumar D, Chakkittukandiyil A, Kothandan R, Selvaraj J, Selvaraj D, "The identification of cianidanol as a selective estrogen receptor beta agonist and evaluation of its neuroprotective effects on Parkinson's disease models", Life Sciences, vol. 333, pp. 122144, 2023.
    Indexing: Scopus, • IF: 5.1
12. Roy D, Balasubramanian S, Kunte PP, Natarajan J, Sola P, Rymbai E, "Roflumilast-loaded nanostructured lipid carriers attenuate oxidative stress and neuroinflammation in Parkinson’s disease model", Journal of Drug Targeting, vol. 33, pp. 127-142, 2023.
    Indexing: Scopus, • IF: 3.9
13. Chakkittukandiyil A, Chakraborty S, Kothandan R, Rymbai E, Muthu SK, Vasu S, Sajini DV, Sugumar D, Mohammad ZB, Jayaram S, Rajagopal K., "Side effects based network construction and drug repositioning of ropinirole as a potential molecule for Alzheimer’s disease: an in-silico, in-vitro, and in-vivo study", Journal of Biomolecular Structure and Dynamics, vol. 42, pp. 10785-10799, 2023.
    Indexing: Scopus, • IF: 2.4
14. Sugumar D, Rymbai E, Vasu S, Selvaraj D, "Nuclear receptors and other molecular targets in type 2 diabetes mellitus", Journal of Applied Pharmaceutical Science, vol. 13, pp. 85-101, 2023.
    Indexing: Scopus,
15. Bhat AS, Singh NA, Rymbai E, Birendra S, Jayaram S, Selvaraj D, "Importance of fibrosis in the pathogenesis of uterine leiomyoma and the promising anti-fibrotic effects of dipeptidyl peptidase-4 and fibroblast activation protein inhibitors in the treatment of uterine leiomyoma", Reproductive Sciences, vol. 30, pp. 1383-1398, 2023.
    Indexing: Scopus, • IF: 2.5
16. Roy D, Balasubramanian S, Krishnamurthy PT, Sola P, Rymbai E, "Phosphodiesterase-4 Inhibition in Parkinson’s Disease: Molecular Insights and Therapeutic Potential", Cellular and Molecular Neurobiology, vol. 42, pp. 10785-10799, 2023.
    Indexing: Scopus, • IF: 4.8
17. Rymbai E, Sugumar D, Krishnamurthy PT, Selvaraj D, Vasu S, Priya S, Jayaram S, "A preliminary study to identify existing drugs for potential repurposing in breast cancer based on side effect profile", Drug Research, vol. 73, pp. 296-303, 2023.
    Indexing: Scopus, • IF: 2.1
18. Mhanasundaram T, Ramachandran V, Bhongiri B, Rymbai E, Xavier RM, Rao GN, Narendar C, "The Promotion of Antioxidant and Anti-Inflammatory Activity by Nrf2 Amplifier is A Potential Technique in Diabetic Wound Healing-A Review", Pharmaceutical Sciences, vol. 29, pp. 255-262, 2022.
    Indexing: Scopus, • IF: 1.5
19. Rymbai E, Sugumar D, Roy D, Selvaraj D, "Role of estrogen receptors in cancer: a special emphasis on the therapeutic potential of estrogen receptor ß.", Pharmaceutical Sciences Asia, vol. 49, pp. 1-17, 2022.
    Indexing: Scopus,
20. Rymbai E, Sugumar D, Selvaraj J, Kothandam R, Selvaraj D, "Modulation of Nrf2 by activation of estrogen receptor ? as a therapeutic strategy to prevent cancer development and overcome inflammation-related drug resistance in breast cancer", Pharmaceutical Sciences, vol. 29, pp. 1-9, 2022.
    Indexing: UGC list, • IF: 1.5
21. Jayaram S, Krishnamurthy PT, Selvaraj D, Nemani SV, Rymbai E, Sugumar D, Bhat AS, Joshi M, Kumar V, "Temporal Unpredictability and Probabilistic Uncertainty Induced Anxiety in the Times of COVID-19 Pandemic", Indian Journal of Pharmaceutical Education and Research, vol. 56, pp. 321-328, 2022.
    Indexing: Scopus,
22. Swathi KP, Jayaram S, Sugumar D, Rymbai E, "Evaluation of anti-inflammatory and anti-arthritic property of ethanolic extract of Clitoria ternatea", Chinese Herbal Medicines, vol. 13, pp. 243-249, 2021.
    Indexing: Scopus, • IF: 8.9
23. Rymbai E, "A Review on the Anti-Viral Activity of Houttuynia cordata: A Possible Herb for the Management and Treatment of COVID-19", Current Research Journal of Pharmaceutical and Allied Sciences, vol. 4, pp. 3-10, 2021.
    Indexing: Others,
24. Deepa S, Rymbai E, Praveen TK, Saravanan J, "Neuroprotective effects of farnesol on motor and cognitive impairment against 3-nitropropionic acid-induced Huntington's disease", Thai Journal of Pharmaceutical Sciences, vol. 41, pp. 16-23. , 2021.
    Indexing: Scopus,
25. Rymbai E, Sugumar D, Saravanan J, Divakar S, "Ropinirole, a potential drug for systematic repositioning based on side effect profile for management and treatment of Breast Cancer", Medical Hypotheses, vol. 144, pp. 110156, 2020.
    Indexing: Scopus, • IF: 0.8
26. Jayaram S, Ramajayam SK, Rymbai E, Sugumar D, "Using link and major system of memory to memorise, remember and recall pharmaceutical sciences better", Indian Journal of Pharmaceutical Education and Research, vol. 54, pp. S438-S441, 2020.
    Indexing: Scopus,
27. Rymbai E, Jayaram S, Sugumar D, Selvaraj D, "Drug Repurposing: A Paradigm Shift in Drug Discovery", International Journal of Applied Pharmaceutical Sciences and Research, vol. 5, pp. 60-68, 2020.
    Indexing: Others,
28. Nanditha R, Saravanan J, Praveen TK, Deepa S, Rymbai E, "Evaluation of anti-cancer, antioxidant and antimicrobial activities of Alstonia scholaris L", Research Journal of Pharmacy and Technology, vol. 13, pp. 4153-4157, 2020.
    Indexing: Google Scholar,
29. Sugumar D, Saravanan J, Emdormi R, Praveen TK, "An update on the role of Nrf2 and its activators in diseases associated with oxidative stress", Indian Journal of Pharmaceutical Sciences, vol. 82, pp. 184-192, 2020.
    Indexing: Google Scholar,
30. Rymbai EM, Chakraborty A, Choudhury R, Verma N, De B, "Review on Chemistry and Therapeutic Activity of the Derivatives of Furan and Oxazole: The Oxygen Containing Heterocycles", Der Pharma Chemica, vol. 11, pp. 20-41, 2019.
    Indexing: Google Scholar,
31. Pooja VW, Saravanan J, Praveen TK, Rymbai E, Deepa S, "Evaluation of aphrodisiac activity of allium sativum in male rats", International Journal of Scientific & Technology Research, vol. 8, pp. 1683-1686., 2019.
    Indexing: Google Scholar,